{"id":3066,"date":"2025-02-10T19:40:44","date_gmt":"2025-02-10T19:40:44","guid":{"rendered":"https:\/\/truthinlabeling.org\/blog\/?p=3066"},"modified":"2025-02-10T19:40:44","modified_gmt":"2025-02-10T19:40:44","slug":"correlations-and-common-sense-the-glutamine-glutamate-cycle-causes-cancer","status":"publish","type":"post","link":"https:\/\/truthinlabeling.org\/blog\/2025\/02\/10\/correlations-and-common-sense-the-glutamine-glutamate-cycle-causes-cancer\/","title":{"rendered":"Correlations and Common Sense: The Glutamine-Glutamate Cycle Causes CANCER"},"content":{"rendered":"\n<p><strong>A guest post by<a href=\"https:\/\/glmcclure.substack.com\/\" target=\"_blank\" rel=\"noreferrer noopener\"> glmcclure<\/a><\/strong><\/p>\n\n\n\n<p>Editor&#8217;s note: glmcclure writes the very informative Substack called Ageddon, you can <a href=\"https:\/\/glmcclure.substack.com\/\" target=\"_blank\" rel=\"noreferrer noopener\">subscribe to it here.<\/a><\/p>\n\n\n\n<p>As a reminder:<\/p>\n\n\n\n<p>1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Glutamine-Glutamate Cycle is involved in most chronic diseases.<\/p>\n\n\n\n<p>2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our foods are LOADED with Manufactured free Glutamates (MfG\u2019s) that overload our bodies with free Glutamates, which in turn affects our Glutamine-Glutamate Cycle.<\/p>\n\n\n\n<p>Here\u2019s today\u2019s Correlation:<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"627\" height=\"651\" src=\"https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image.png\" alt=\"\" class=\"wp-image-3067\" srcset=\"https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image.png 627w, https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image-289x300.png 289w\" sizes=\"auto, (max-width: 627px) 100vw, 627px\" \/><\/figure>\n\n\n\n<p><a href=\"https:\/\/cancercontrol.cancer.gov\/ocs\/statistics#\">Source<\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"772\" height=\"721\" src=\"https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image-1.png\" alt=\"\" class=\"wp-image-3068\" srcset=\"https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image-1.png 772w, https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image-1-300x280.png 300w, https:\/\/truthinlabeling.org\/blog\/wp-content\/uploads\/2025\/02\/image-1-768x717.png 768w\" sizes=\"auto, (max-width: 767px) 89vw, (max-width: 1000px) 54vw, (max-width: 1071px) 543px, 580px\" \/><\/figure>\n\n\n\n<p><a href=\"https:\/\/globalizationandhealth.biomedcentral.com\/articles\/10.1186\/s12992-023-00990-1\/figures\/1\">SOURCE<\/a><\/p>\n\n\n\n<p>Here are selected comments from Google AI for a search of \u201cGlutamine-glutamate cycle cancer\u201d (Some comments bolded by me):<\/p>\n\n\n\n<p><strong>\u201cAI Overview<\/strong><\/p>\n\n\n\n<p>The glutamine-glutamate cycle is&nbsp;<strong>a metabolic process that involves the conversion of glutamine to glutamate in cancer cells<\/strong>:\u201d<\/p>\n\n\n\n<p><strong>Cancer cells have an increased dependency on glutamine<\/strong>, which is thought to be a&nbsp;<strong>result of the Warburg effect<\/strong>. (See more about the Warburg effect below)<\/p>\n\n\n\n<p><strong>Targeting the glutamine-glutamate cycle is a potential cancer therapy:<\/strong><\/p>\n\n\n\n<p><strong>Targeting glutamate secretion<\/strong><\/p>\n\n\n\n<p>In some cancers,&nbsp;<strong>glutamate secretion stimulates tumor growth<\/strong>. The FDA-approved drug&nbsp;<strong>riluzole suppresses glutamate secretion<\/strong>&nbsp;and reduces the proliferation of melanoma cells.<\/p>\n\n\n\n<p><strong>Supplemental glutamine can stimulate the immune system, which can decrease tumor growth<\/strong>.\u201d (<a href=\"https:\/\/www.google.com\/search?q=Glutamine-glutamate+cycle+cancer&amp;oq=Glutamine-glutamate+cycle+cancer&amp;gs_lcrp=EgZjaHJvbWUqBggAEEUYOzIGCAAQRRg70gEIMTUwN2owajeoAgCwAgA&amp;sourceid=chrome&amp;ie=UTF-8\">SOURCE<\/a>)<\/p>\n\n\n\n<p>So what is this \u201cWarburg Effect\u201d they speak of? Here\u2019s the Google AI search for \u201cglutamine-glutamate cycle Warburg effect\u201d (Highlights by me):<\/p>\n\n\n\n<p>\u201cThe &#8220;<strong>glutamine-glutamate cycle&#8221; plays a significant role in the Warburg effect<\/strong>&nbsp;by&nbsp;<strong>providing cancer cells with a crucial source of carbon and nitrogen through the conversion of glutamine to glutamate<\/strong>, \u2026\u201d (<a href=\"https:\/\/www.google.com\/search?q=glutamine-glutamate+cycle+warburg+affect&amp;oq=glutamine-glutamate+cycle+warburg+affect&amp;gs_lcrp=EgZjaHJvbWUyBggAEEUYOdIBCTExNTkxajBqN6gCALACAA&amp;sourceid=chrome&amp;ie=UTF-8\">SOURCE<\/a>)<\/p>\n\n\n\n<p>Now, if you think about it, excess free Glutamate (as occurs in massive amounts in UPF\u2019s (Ultra-Processed Foods) actually puts the Warburg Effect on steroids.<\/p>\n\n\n\n<p>Our natural glutamine-glutamate cycle converts glutamine to glutamate and back again to glutamine at a rate that our body naturally needs for normal cell metabolism.<\/p>\n\n\n\n<p>However, when we eat free Glutamates, it creates a much higher level of Glutamates in our system than we can use for natural cell metabolism.<\/p>\n\n\n\n<p>Cancer cells, though, LOVE this stuff! It is literally what allows them to continue to live and grow.<\/p>\n\n\n\n<p>Think about that.<\/p>\n\n\n\n<p>And avoid the food additives below like the Plague they are!<\/p>\n\n\n\n<p>They are, or create, excessive free glutamate, which in turn alters the glutamine-glutamate cycle in the body.<\/p>\n\n\n\n<p>Which in turn, creates multiple chronic diseases, only one of which is cancer.<\/p>\n\n\n\n<p>More to come in the future.<\/p>\n\n\n\n<p><strong>\u201cNames of ingredients that&nbsp;<\/strong><em><strong>always<\/strong><\/em><strong>&nbsp;contain free glutamate:<\/strong><\/p>\n\n\n\n<p>Glutamic acid (E 620)<br>Glutamate (E 620)<br>Monosodium glutamate (E 621)<br>Monopotassium glutamate (E 622)<br>Calcium glutamate (E 623)<br>Monoammonium glutamate (E 624)<br>Magnesium glutamate (E 625)<br>Natrium glutamate<br>anything \u201cHydrolyzed\u201d<br>any \u201cHydrolyzed protein\u201d<br>Calcium caseinate, Sodium caseinate<br>Yeast extract, Torula yeast<br>Yeast food, Yeast nutrient, Nutritional yeast<br>Autolyzed yeast, Brewer&#8217;s yeast<br>Gelatin<br>Textured protein<br>Whey protein<br>Whey protein concentrate<br>Whey protein isolate<br>Soy protein<br>Soy protein concentrate<br>Soy protein isolate<br>anything \u201cProtein\u201d<br>anything \u201cProtein fortified\u201d<br>anything &#8220;Protein concentrate&#8221;<br>anything &#8220;Protein isolate&#8221;<br>Zinc proteinate<br>anything &#8220;Proteinate&#8221;<br>Soy sauce<br>Soy sauce extract<br>Protease<br>anything \u201cEnzyme modified\u201d<br>anything containing \u201cEnzymes\u201d<br>anything \u201cFermented\u201d<br>Vetsin<br>Ajinomoto<\/p>\n\n\n\n<p><strong>Names of ingredients that often contain or produce free glutamate during processing:<\/strong><\/p>\n\n\n\n<p>Carrageenan (E 407)<br>Bouillon and broth<br>Stock<br>any \u201cFlavors\u201d or \u201cflavoring\u201d<br>Natural flavor<br>Maltodextrin<br>Oligodextrin<br>Citric acid, Citrate (E 330)<br>anything \u201cUltra-pasteurized\u201d<br>Barley malt<br>Malted barley<br>Pectin (E 440)<br>Malt extract<br>Seasonings<br>Soy milk<\/p>\n\n\n\n<p><strong>The following are ingredients suspected of containing or creating sufficient free glutamate to serve as reaction triggers in HIGHLY SENSITIVE people:<\/strong><\/p>\n\n\n\n<p>Corn starch<br>Corn syrup<br>Modified food starch<br>Lipolyzed butter fat<br>Dextrose<br>Rice syrup<br>Brown rice syrup<br>Milk powder<br>Reduced fat milk (skim; 1%; 2%)<br>most things \u201cLow fat\u201d or \u201cNo fat\u201d<br>anything \u201cEnriched\u201d<br>anything \u201cVitamin enriched\u201d<br>anything \u201cPasteurized\u201d<br>Annatto<br>Vinegar<br>Balsamic vinegar<br>certain Amino Acid Chelates (Citrate, Aspartate, and Glutamate are used as chelating agents with mineral supplements.)<\/p>\n\n\n\n<p><strong>The following work synergistically with free glutamate to enhance flavor. If they are present for flavoring, so is free glutamate:<\/strong><\/p>\n\n\n\n<p>Disodium 5\u2019-guanylate (E 627) \/ Disodium 5\u2019-inosinate (E-631) \/ Disodium 5&#8242;-ribonucleotides (E 635)\u201d&nbsp;<a href=\"https:\/\/www.truthinlabeling.org\/names.html\">Truthinlabeliing.org<\/a><\/p>\n<div style=\"margin-top: 0px; margin-bottom: 0px;\" class=\"sharethis-inline-share-buttons\" ><\/div>","protected":false},"excerpt":{"rendered":"<p>A guest post by glmcclure Editor&#8217;s note: glmcclure writes the very informative Substack called Ageddon, you can subscribe to it here. As a reminder: 1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;The Glutamine-Glutamate Cycle is involved in most chronic diseases. 2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Our foods are LOADED with Manufactured free Glutamates (MfG\u2019s) that overload our bodies with free Glutamates, which in turn affects our Glutamine-Glutamate &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/truthinlabeling.org\/blog\/2025\/02\/10\/correlations-and-common-sense-the-glutamine-glutamate-cycle-causes-cancer\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Correlations and Common Sense: The Glutamine-Glutamate Cycle Causes CANCER&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3066","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/posts\/3066","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/comments?post=3066"}],"version-history":[{"count":2,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/posts\/3066\/revisions"}],"predecessor-version":[{"id":3070,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/posts\/3066\/revisions\/3070"}],"wp:attachment":[{"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/media?parent=3066"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/categories?post=3066"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/truthinlabeling.org\/blog\/wp-json\/wp\/v2\/tags?post=3066"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}