Who are the ‘Glutes’?

For years, the Truth in Labeling Campaign has been calling them the “Glutes,” a name that many now recognize as being those who make money selling their poisons hidden in food. We gave them a name because we want you to know them and start talking about them, and it’s hard to talk about someone or something if it doesn’t have a name.

The founder and chief operating officer of this loosely knit operation is Ajinomoto, the world’s largest producer of monosodium glutamate. Ajinomoto designs and bankrolls its research, bragging of the millions it’s spending on public relations to “clear MSG’s bad name.” Their goal is to counter the fact that every day more and more people are suffering reactions to MSG and other flavor enhancers that contain MSG’s toxic manufactured free glutamate (MfG) by plastering the world with propaganda that MSG has gotten a bad rap.

Without the researchers who execute their double-blind studies using excitotoxic, brain damaging placebos, without the food technologists who incorporate MfG into thousands of processed foods, without the manufacturers that use MSG in their products so they can skimp on quality — aided by the grocery outlets that sell their products — and without the “public servants” at the FDA who for 50 years have turned their backs on research that clearly demonstrates MSG has toxic potential while endorsing the out and out lie that MSG is safe for use in food, MSG would have long ago been banned. And it can be done. As recently as 2018 the FDA acted to no longer allow the use of seven flavoring substances and flavor enhancers deemed dangerous.

Those are the Glutes: the people who work to keep MSG flowing without mentioning that they work for the producer of MSG when signing off on their work.

Who are the ‘Glutes’?

For years, the Truth in Labeling Campaign has been calling them the “Glutes,” a name that many now recognize as being those who make money selling their poisons hidden in food. We gave them a name because we want you to know them and start talking about them, and it’s hard to talk about someone or something if it doesn’t have a name.

The founder and chief operating officer of this loosely knit operation is Ajinomoto, the world’s largest producer of monosodium glutamate. Ajinomoto designs and bankrolls its research, bragging of the millions it’s spending on public relations to “clear MSG’s bad name.” Their goal is to counter the fact that every day more and more people are suffering reactions to MSG and other flavor enhancers that contain MSG’s toxic manufactured free glutamate (MfG) by plastering the world with propaganda that MSG has gotten a bad rap.

Without the researchers who execute their double-blind studies using excitotoxic, brain damaging placebos, without the food technologists who incorporate MfG into thousands of processed foods, without the manufacturers that use MSG in their products so they can skimp on quality — aided by the grocery outlets that sell their products — and without the “public servants” at the FDA who for 50 years have turned their backs on research that clearly demonstrates MSG has toxic potential while endorsing the out and out lie that MSG is safe for use in food, MSG would have long ago been banned. And it can be done. As recently as 2018 the FDA acted to no longer allow the use of seven flavoring substances and flavor enhancers deemed dangerous.

Those are the Glutes: the people who work to keep MSG flowing without mentioning that they work for the producer of MSG when signing off on their work.

‘Likely culprit’ in celiac disease hidden in processed foods

Why is Ajinomoto trying so hard to keep transglutaminase unlabeled?

Over the past few decades celiac disease (CD) has morphed into a “major public health problem.” Along with it, other autoimmune conditions such as diabetes, rheumatoid arthritis, inflammatory bowel disease and psoriasis, are also topping the charts as very common disorders with dozens of heavily advertised drugs created to treat them.

If you ask why, the knee-jerk response is typically that better testing has uncovered all these otherwise undisclosed conditions. But does that really explain things? And it certainly doesn’t take into consideration what experts refer to as large numbers of people with undiagnosed autoimmune diseases, especially CD.

Back in 2015 two researchers with expertise in metabolic diseases, Aaron Lerner, a professor at Tel Aviv University, and Torsten Matthias, affiliated with the AESKU.KIPP Institute in Germany, first sounded the alarm on a largely unknown, widely used food additive – an enzyme called transglutaminase (TG). At that time, they proposed a “hypothesis” linking TG used in food processing to celiac and other autoimmune diseases. Four years later, however, the pair stated that further research and observations have closed the “gaps” in our understanding of how TG is an “inducer of celiac disease.”   

Big Food’s favorite find to ‘glue’ things together

Transglutaminase, a.k.a. “meat glue,” is the darling of Big Food for lots of reasons: it can glue together scraps of fish, chicken and meat into whole-looking cuts (often called “Frankenmeats”); extend the shelf life of processed foods (even pasta); improve “texture,” especially in low-salt, low-fat products; make breads and pastries (particularly gluten-free ones) rise better, and, as one manufacturer puts it, allow for use of things that would ordinarily be tossed out — unappetizing leftovers and scraps of food that would “otherwise be considered waste ingredients, creating an added-value product.”

But more than just turning “waste ingredients” into new food products, there are a host of other reasons why you should do your best to steer clear of meat glue.

‘Tight junction dysfunction’

The 2015 research published by Lerner and Matthias detailed how certain food additives may be behind the steady rise of autoimmune diseases due to something called “tight junction dysfunctions,” which can set the stage for a wide variety of serious ailments, calling out transglutaminase as one of the commonly used food additives that can enhance “intestinal junction leakage.”

A subsequent study in 2019 recognized transglutaminase as a “likely culprit” in celiac disease.

In 2020, Lerner and Matthias published yet another paper on transglutaminase and celiac disease, calling it a “potential public health concern” and saying that they hope their review will “encourage clinical, scientific and regulatory debates on (its) safety to protect the public.”

Despite all the warnings and additional research, use of the enzyme is booming, and all its food uses are now considered GRAS (generally recognized as safe) by the FDA.

TG and MSG

The similarities between MSG and transglutaminase are quite noteworthy. Not only is the enzyme manufactured in great quantities by Ajinomoto (as is MSG) but the way TG is promoted by the company is remarkably similar to its long-running propaganda campaign claiming that MSG is a safe ingredient.

For example, Ajinomoto states on its websites and elsewhere that both MSG and TG are “found in food naturally,” are “safe,” used in many countries and considered GRAS in the U.S. by the FDA. And just as MSG supposedly in no way causes serious reactions, the company says that TG in no way causes celiac disease – in fact, under some circumstances the TG added to food can actually help CD patients, Ajinomoto says.

While transglutaminase is found naturally in the human body (as is glutamate), there is a significant difference between microbial TG (the manufactured additive) and “our own transglutaminase” says Lerner.  (Just as there is a major difference between manufactured MSG and the glutamate in your body).

That’s because the tissue TG produced in the body “has a different structure (from) the microbial sort, which allows its activity to be tightly controlled. Microbial transglutaminase itself could also increase intestinal permeability,” he says, “by directly modifying proteins that hold together the intestinal barrier.”

The FDA has “no questions”

While once the FDA pretended to look into the safety of a product before granting it GRAS status, not even that is done any more.  Now a company simply turns in a statement that a product should be referred to as GRAS, and it’s done.

Starting in 1998 Ajinomoto filed four notices of “self-determined” GRAS status for TG with the FDA. The first was to use TG in seafood. In 1999 they sent in more intended uses for hard and soft cheeses, yogurt, and “vegetable protein dishes/veggie burgers/meat substitutes.” In 2000 Ajinomoto sent another notice to the FDA regarding using transglutaminase in pasta, bread, pastries, ready-to-eat cereal, pizza dough and “grain mixtures.”

And in 2002, Ajinomoto asked that anything else it might have previously overlooked, referred to as “use in food in general,” be given GRAS status. None of these GRAS notices elicited any objections from the FDA.  Nothing that Big Food asks for is even questioned any more.

Included in the 2001 “everything else” notification from Ajinomoto were some details of a 30-day toxicity study using beagles. Despite findings that included dogs that had developed a pituitary gland cyst, discoloration of the lungs, an enlarged uterus and “significantly” lower prostate weights, all that was considered “incidental and unrelated” to TG. Why they bothered to include a study that shows that their product causes harm to the animals studied can only be understood if you know how Ajinomoto operates.  Having done a study, they can later refer to the study that they did as though it proved that their product was “safe,” knowing that no one will challenge them. Such claims have great propaganda value.

The FDA had “no questions.”

Transglutaminase, here, there and everywhere

Lerner and Matthias have been warning for years about TG hidden in processed foods, saying it’s “unlabeled and hidden from public knowledge.” As we mentioned in another blog on TG several weeks ago, aside from “formed” meat products sold in supermarkets in the U.S. where the enzyme must be called out on the ingredient statement, TG can easily go undercover. 

And Ajinomoto has even added its own tips to help food manufacturers avoid labeling by providing an explanation of how TG is just a “processing aid,” as well as making available a letter authored by a law firm in Germany stating that aside from use in “formed” meat or fish, transglutaminase is “no ingredient” and as such in the EU does not have to be included on a food label. In fact, the lawyers go so far as to state that if a substance (such as TG) is “without any function in the finished product,” listing it on the ingredient label can “mislead the consumer.”

The FDA told us that if TG is used as a “processing aid” it’s considered an “incidental additive” and is “exempted from ingredient labeling.”

Even organic products aren’t safe from TG, as TG is considered A-OK to use it in organic foods, falling under the “allowed” generic category of “enzymes” on the USDA “National list of allowed and prohibited substances” in organic food and farming.

Perhaps the most devious use of this enzyme is to improve the appearance of gluten-free bakery products. Manufactured, microbial transglutaminase “functionally imitates” natural-tissue TG, which is known to be an autoantigen (a “self” antigen, reacting to something produced by the body that provokes an immune response) in those who suffer from celiac disease.  

Steering clear of transglutaminase

The TG story could very well be called a case against processed foods, as the only sure-fire way to avoid this gut-wrenching enzyme is to make/cook all your food from scratch. That being a very unlikely prospect these days, the next best thing is to avoid the following:

  • Low-fat and low-salt products, especially dairy and dairy substitutes;
  • Chicken nuggets, along with any other “formed” meat products;
  • Expensive cuts of meat being sold much cheaper than they should be (that especially is true for restaurants);
  • Sushi from unreliable sources, formed fish sticks and balls;
  • Veggie and tofu burgers; and
  • Cheaply produced pasta (TG is said to help when using “damaged wheat flour”).

When asked what he would consider to be an important take-away regarding transglutaminase, Professor Lerner told us that it would be for the FDA to “reconsider the classification of (manufactured) TG as GRAS.”

Released documents expose that Ajinomoto paid the U.S. Dept. of Agriculture over half a million dollars to do a study designed to prove that consuming MSG is good for you

Last December we revealed a remarkable finding, a 2010 press release issued by Ajinomoto telling about the company’s cozy partnership with the U.S. Department of Agriculture to study MSG.

At that time, we tracked down and sent some questions to the scientist named in the release, Dr. Kevin Laugero, who is still affiliated with the USDA/ARS (Agricultural Research Service). When we didn’t hear back from him, we took the next step, a Freedom of Information Act request with the USDA.

We recently received a response from the USDA. Here’s what we learned in a 53-page release of documents, many of them invoices from the USDA to Ajinomoto.

  • Ajinomoto, possibly the world’s largest manufacturer of MSG, paid the USDA a total of $674,000 to conduct a three-year “study” on the “effects of ingesting MSG on energy balance and eating behavior.”  The hypothesis proposed was that daily consumption of MSG will “reduce body weight rebound.”
  • Ajinomoto, known as “the cooperator” in the official “statement of work” filled out by the USDA, was given a wire routing number to zip those funds into an account at Citibank.
  • The original budget of $598,653 was increased twice to “expand subject recruitment efforts,” hire a staff recruiter, project manager and up the stipend paid to volunteers, which was originally $580 per person for a 25-week commitment.

Although Dr. Laugero finally did reply, he would only say that the Ajinomoto glutamate research project was completed and that scientists have analyzed the data, which have not been published. “I can’t really comment on the results.” he said.

But by far the most interesting part of the documents we received has to do with the “research plan,” a study to be produced by three USDA researchers – including Dr. Laugero.  The outline describes a six-month scheme for psychological and metabolic evaluations, cognitive testing, multiple blood draws, saliva samples, “snack food buffets,” mental stress tests, and MRI brain scans that collected data on the subject’s “neural responses to food cues,” none of which appear to be relevant to energy balance and eating behavior.  Volunteers were sent questionnaires, and for the MSG test group there would be consumption of MSG (supplied as a broth powder) prior to their breakfast, lunch and dinner – called the “intervention phase.”  

But evidently something went wrong, as the study was never published. Since we know the Glutes never publish anything that might suggest that MSG is toxic, and since the USDA was not even pretending to do an independent study, apparently when the results didn’t come out as desired the report of the study vanished. If not for the twelve-year-old press release we found online that tipped us off, no one outside of the USDA would know about this “partnership” payout.

One might ask why this study was done in the first place? And why done by the USDA?

We think we may know at least part of the answer.

Two years before the USDA/Ajinomoto joint venture, a study from the University of North Carolina clearly linked MSG consumption in people to weight gain. According to epidemiologist Dr. Ka He, those who consume large amounts of MSG increase their risk of being overweight by a whopping 175 percent.

To counter that, Ajinomoto jumped in with a rodent study that was published in the journal Physiology & Behavior, concluding that rats who drank MSG spiked water were lean and healthy. But perhaps comparing their lab rats to humans didn’t seem as effective – at least publicity wise.

So, why not collect a group of human lab animals to study, and have the good name of the USDA associated with Ajinomoto and the safety of MSG?  Ajinomoto found the USDA more than willing to play along.

As we said last year, this is a stunning example of how closely connected industry is with our so-called watchdog federal agencies.

Those interested in learning more about agency/industry cooperation will find interesting material at Industry’s FDAhttps://www.truthinlabeling.org/assets/industrys_fda_final.pdf. Those with interest in methods used by the Glutes to come to the foregone conclusion that MSG is a harmless food additive can access How the “MSG is safe” game is playedhttps://www.truthinlabeling.org/safe.html

‘Likely culprit’ in celiac disease hidden in processed foods

Why is Ajinomoto trying so hard to keep transglutaminase unlabeled?

Over the past few decades celiac disease (CD) has morphed into a “major public health problem.” Along with it, other autoimmune conditions such as diabetes, rheumatoid arthritis, inflammatory bowel disease and psoriasis, are also topping the charts as very common disorders with dozens of heavily advertised drugs created to treat them.

If you ask why, the knee-jerk response is typically that better testing has uncovered all these otherwise undisclosed conditions. But does that really explain things? And it certainly doesn’t take into consideration what experts refer to as large numbers of people with undiagnosed autoimmune diseases, especially CD.

Back in 2015 two researchers with expertise in metabolic diseases, Aaron Lerner, a professor at Tel Aviv University, and Torsten Matthias, affiliated with the AESKU.KIPP Institute in Germany, first sounded the alarm on a largely unknown, widely used food additive – an enzyme called transglutaminase (TG). At that time, they proposed a “hypothesis” linking TG used in food processing to celiac and other autoimmune diseases. Four years later, however, the pair stated that further research and observations have closed the “gaps” in our understanding of how TG is an “inducer of celiac disease.”   

Big Food’s favorite find to ‘glue’ things together

Transglutaminase, a.k.a. “meat glue,” is the darling of Big Food for lots of reasons: it can glue together scraps of fish, chicken and meat into whole-looking cuts (often called “Frankenmeats”); extend the shelf life of processed foods (even pasta); improve “texture,” especially in low-salt, low-fat products; make breads and pastries (particularly gluten-free ones) rise better, and, as one manufacturer puts it, allow for use of things that would ordinarily be tossed out — unappetizing leftovers and scraps of food that would “otherwise be considered waste ingredients, creating an added-value product.”

But more than just turning “waste ingredients” into new food products, there are a host of other reasons why you should do your best to steer clear of meat glue.

‘Tight junction dysfunction’

The 2015 research published by Lerner and Matthias detailed how certain food additives may be behind the steady rise of autoimmune diseases due to something called “tight junction dysfunctions,” which can set the stage for a wide variety of serious ailments, calling out transglutaminase as one of the commonly used food additives that can enhance “intestinal junction leakage.”

A subsequent study in 2019 recognized transglutaminase as a “likely culprit” in celiac disease.

In 2020, Lerner and Matthias published yet another paper on transglutaminase and celiac disease, calling it a “potential public health concern” and saying that they hope their review will “encourage clinical, scientific and regulatory debates on (its) safety to protect the public.”

Despite all the warnings and additional research, use of the enzyme is booming, and all its food uses are now considered GRAS (generally recognized as safe) by the FDA.

TG and MSG

The similarities between MSG and transglutaminase are quite noteworthy. Not only is the enzyme manufactured in great quantities by Ajinomoto (as is MSG) but the way TG is promoted by the company is remarkably similar to its long-running propaganda campaign claiming that MSG is a safe ingredient.

For example, Ajinomoto states on its websites and elsewhere that both MSG and TG are “found in food naturally,” are “safe,” used in many countries and considered GRAS in the U.S. by the FDA. And just as MSG supposedly in no way causes serious reactions, the company says that TG in no way causes celiac disease – in fact, under some circumstances the TG added to food can actually help CD patients, Ajinomoto says.

While transglutaminase is found naturally in the human body (as is glutamate), there is a significant difference between microbial TG (the manufactured additive) and “our own transglutaminase” says Lerner.  (Just as there is a major difference between manufactured MSG and the glutamate in your body).

That’s because the tissue TG produced in the body “has a different structure (from) the microbial sort, which allows its activity to be tightly controlled. Microbial transglutaminase itself could also increase intestinal permeability,” he says, “by directly modifying proteins that hold together the intestinal barrier.”

The FDA has “no questions”

While once the FDA pretended to look into the safety of a product before granting it GRAS status, not even that is done any more.  Now a company simply turns in a statement that a product should be referred to as GRAS, and it’s done.

Starting in 1998 Ajinomoto filed four notices of “self-determined” GRAS status for TG with the FDA. The first was to use TG in seafood. In 1999 they sent in more intended uses for hard and soft cheeses, yogurt, and “vegetable protein dishes/veggie burgers/meat substitutes.” In 2000 Ajinomoto sent another notice to the FDA regarding using transglutaminase in pasta, bread, pastries, ready-to-eat cereal, pizza dough and “grain mixtures.”

And in 2002, Ajinomoto asked that anything else it might have previously overlooked, referred to as “use in food in general,” be given GRAS status. None of these GRAS notices elicited any objections from the FDA.  Nothing that Big Food asks for is even questioned any more.

Included in the 2001 “everything else” notification from Ajinomoto were some details of a 30-day toxicity study using beagles. Despite findings that included dogs that had developed a pituitary gland cyst, discoloration of the lungs, an enlarged uterus and “significantly” lower prostate weights, all that was considered “incidental and unrelated” to TG. Why they bothered to include a study that shows that their product causes harm to the animals studied can only be understood if you know how Ajinomoto operates.  Having done a study, they can later refer to the study that they did as though it proved that their product was “safe,” knowing that no one will challenge them. Such claims have great propaganda value.

The FDA had “no questions.”

Transglutaminase, here, there and everywhere

Lerner and Matthias have been warning for years about TG hidden in processed foods, saying it’s “unlabeled and hidden from public knowledge.” As we mentioned in another blog on TG several weeks ago, aside from “formed” meat products sold in supermarkets in the U.S. where the enzyme must be called out on the ingredient statement, TG can easily go undercover. 

And Ajinomoto has even added its own tips to help food manufacturers avoid labeling by providing an explanation of how TG is just a “processing aid,” as well as making available a letter authored by a law firm in Germany stating that aside from use in “formed” meat or fish, transglutaminase is “no ingredient” and as such in the EU does not have to be included on a food label. In fact, the lawyers go so far as to state that if a substance (such as TG) is “without any function in the finished product,” listing it on the ingredient label can “mislead the consumer.”

The FDA told us that if TG is used as a “processing aid” it’s considered an “incidental additive” and is “exempted from ingredient labeling.”

Even organic products aren’t safe from TG, as TG is considered A-OK to use it in organic foods, falling under the “allowed” generic category of “enzymes” on the USDA “National list of allowed and prohibited substances” in organic food and farming.

Perhaps the most devious use of this enzyme is to improve the appearance of gluten-free bakery products. Manufactured, microbial transglutaminase “functionally imitates” natural-tissue TG, which is known to be an autoantigen (a “self” antigen, reacting to something produced by the body that provokes an immune response) in those who suffer from celiac disease.  

Steering clear of transglutaminase

The TG story could very well be called a case against processed foods, as the only sure-fire way to avoid this gut-wrenching enzyme is to make/cook all your food from scratch. That being a very unlikely prospect these days, the next best thing is to avoid the following:

  • Low-fat and low-salt products, especially dairy and dairy substitutes;
  • Chicken nuggets, along with any other “formed” meat products;
  • Expensive cuts of meat being sold much cheaper than they should be (that especially is true for restaurants);
  • Sushi from unreliable sources, formed fish sticks and balls;
  • Veggie and tofu burgers; and
  • Cheaply produced pasta (TG is said to help when using “damaged wheat flour”).

When asked what he would consider to be an important take-away regarding transglutaminase, Professor Lerner told us that it would be for the FDA to “reconsider the classification of (manufactured) TG as GRAS.”

Something to think about: The IGTC

History tells us that in 1969, the International Glutamate Technical Committee (IGTC) was founded as an association of companies engaged in the manufacture, sale and commercial use of glutamates. It sponsored, gathered, and disseminated research on the use and safety of monosodium glutamate; designed and implemented research protocols and provided financial assistance to researchers; promoted acceptance of monosodium glutamate as a food ingredient and represented members’ collective interests. Those collective interests were to sell monosodium glutamate.  It would appear that the IGTC was the brainchild of Ajinomoto Co., a leading manufacturer of monosodium glutamate. Or possibly Andrew Ebert, long time chairman of the IGTC, thought up the whole thing.  Ebert had been with Minnesota Mining and Minerals when they were producing MSG.

It was reported in 1994 that the IGTC was an association composed of physicians and/or scientists either employed by producers or users of glutamic acid and its salts, or doing research on it in university laboratories. Its annual budget was $250,000. Membership was $2,000/year, with Ajinomoto making up any shortfall between member-provided funds and that quarter-million.

In 1977, the IGTC spun off The Glutamate Association, with both organizations having close ties to the Robert H. Kellen Company of Atlanta, Ga. and Washington, DC.  Kellen is a trade organization and association management firm that specializes in the food, pharmaceutical, and healthcare industries. In 1992, Andrew (Andy) Ebert, Ph.D., chairman of the IGTC, was also senior vice president of The Kellen Company.

Once established, the IGTC assembled a cadre of scientists and others who conducted research for them and/or spoke publicly about the safety of monosodium glutamate. In the 1970s and 1980s, research sponsors were acknowledged.

The names of researchers Altman, Anantharaman, Auer, Bunyan, Ebert, Fernstrom, Filer, Garattini, Geha, Germano, Giacometti, Goldschmiedt, Heywood, Iwata, Kelly, Kenney, Kerr, Matsuzawa, Morselli, Newman, Owen, Patterson, Pulce, Reynolds, Saxon, Schiffman, Simon, Stegink, Stevenson, Takasaki, Tarasoff, Williams, Woessner, and Yang were notable, although there were others. In the late 1990s the names Torii, Shi, Jinap and Hajeb were added to the roster.

Steve Taylor deserves special mention. Although a prominent representative of the glutamate industry, he’s not included with the others because his ties to the IGTC have not openly been acknowledged. Although Taylor has repeatedly spoken out about the safety of MSG, only once to our knowledge has he acknowledged his ties to the IGTC.

When he introduces himself, he typically refers to his University of Nebraska affiliation, but not to the fact that he’s an agent of the IGTC.

Until he was mentioned to the FDA as having been responsible for supplying placebos containing excitotoxic aspartic acid (in aspartame) to the researchers conducting glutamate-safety double-blind studies for him, Ebert had been key to the research operations of the IGTC. This professionally respected pharmacologist and toxicologist had been with the IGTC from the beginning, recruiting researchers to carry out the research designed for them. In each case, that research has enabled Ebert’s people to proclaim (without justification) that a new study has demonstrated that monosodium glutamate is a harmless food additive.

Ebert was the face of the IGTC, and his influence can still be felt at every level. He’s served on the FDA Food Advisory Committee; the Grocery Manufacturers of America (Technical Committee on Food Protection, the Codex Subcommittee on Food Additives and the GRAS-FASEB Monograph Committee); the National Food Processors Association; the Institute of Food Technology (Technology Toxicology and Safety Evaluation Division, and Scientific Lecturer); the National Research Council of the National Academy of Sciences Assembly of Life Sciences (Food and Nutrition Board: the Committee on Food Protection, and the GRAS List Survey); the AMA (Industry Liaison Panel); the FAO/WHO Codex Alimentarius Food Standards Program as an industry observer; and the International Food Additives Council as executive director.

As a food industry pharmacologist and toxicologist, Ebert has provided scientific and technical expertise for programs of many associations managed by The Kellen Company.

It looks like since he was exposed for supplying excitotoxin-containing placebos to his researchers, Ebert no longer sits as chairman of the IGTC. 

In 2009, his name appeared as being on the IGTC Executive Committee. His move from the glutamate industry limelight coincided with the posting of information on the Truth in Labeling Campaign website about his role in designing the IGTC’s “scientific” studies and supplying aspartame-laced placebos (placebos that cause reactions similar, if not identical, to those caused by MSG) to his researchers. Toward the end of the 1990s, we began to see the names of Takeshi Kimura and Yoshi-hisa Sugita, Ph.D., associated with the IGTC. Both Kimura and Sugita came from Ajinomoto. 

Jumping ahead to 2022, it looked like the IGTC had moved its offices to Brussels, with Michael Rogers, IGTC chairman, leaving The Glutamate Association and its International Glutamate Information Service (IGIS) to run Ajinomoto’s U.S. operation while the IGTC continues to focus on whatever it will take (no holds barred) to keep MSG profitable. According to the Global Civil Society Database the IGTC’s aims are to “study, assemble and disseminate scientific data and information related to all aspects of the safety, quality and use of glutamate and its salts, particularly monosodium glutamate with a particular emphasis on their use in foods for human beings; promote the uses of glutamates as food ingredients especially on an international level.”  The six organizations that carry out its work are:

EUROPE – PARIS
European Committee for Umami (ECU)

JAPAN – TOKYO
SOUTH KOREA-SEOUL
Amino Acids Seasoning Alliance of Northeast Asia (ASANA)

REPUBLIC OF CHINA – TAIPEI

Taiwan Amino Acid Manufacturers Association ROC (TAAMA)

SOUTH AMERICA – SAO PAULO

Institute for Glutamate Sciences in South America (IGSSA)

SOUTHEAST ASIA – BANGKOK

Regional Committee for Glutamate Sciences (RCGS)

U.S.A. – WASHINGTON, DC

The Glutamate Association United States (TGA)

The IGTC no longer sponsors studies alleging to demonstrate the safety of MSG.  Instead, they sponsor consensus meetings to which they send delegates who discuss the safety of MSG and submit reports of their meetings to any media that will take them.

Released documents expose that Ajinomoto paid the U.S. Dept. of Agriculture over half a million dollars to do a study designed to prove that consuming MSG is good for you

Last December we revealed a remarkable finding, a 2010 press release issued by Ajinomoto telling about the company’s cozy partnership with the U.S. Department of Agriculture to study MSG.

At that time, we tracked down and sent some questions to the scientist named in the release, Dr. Kevin Laugero, who is still affiliated with the USDA/ARS (Agricultural Research Service). When we didn’t hear back from him, we took the next step, a Freedom of Information Act request with the USDA.

We recently received a response from the USDA. Here’s what we learned in a 53-page release of documents, many of them invoices from the USDA to Ajinomoto.

  • Ajinomoto, possibly the world’s largest manufacturer of MSG, paid the USDA a total of $674,000 to conduct a three-year “study” on the “effects of ingesting MSG on energy balance and eating behavior.”  The hypothesis proposed was that daily consumption of MSG will “reduce body weight rebound.”
  • Ajinomoto, known as “the cooperator” in the official “statement of work” filled out by the USDA, was given a wire routing number to zip those funds into an account at Citibank.
  • The original budget of $598,653 was increased twice to “expand subject recruitment efforts,” hire a staff recruiter, project manager and up the stipend paid to volunteers, which was originally $580 per person for a 25-week commitment.

Although Dr. Laugero finally did reply, he would only say that the Ajinomoto glutamate research project was completed and that scientists have analyzed the data, which have not been published. “I can’t really comment on the results.” he said.

But by far the most interesting part of the documents we received has to do with the “research plan,” a study to be produced by three USDA researchers – including Dr. Laugero.  The outline describes a six-month scheme for psychological and metabolic evaluations, cognitive testing, multiple blood draws, saliva samples, “snack food buffets,” mental stress tests, and MRI brain scans that collected data on the subject’s “neural responses to food cues,” none of which appear to be relevant to energy balance and eating behavior.  Volunteers were sent questionnaires, and for the MSG test group there would be consumption of MSG (supplied as a broth powder) prior to their breakfast, lunch and dinner – called the “intervention phase.”  

But evidently something went wrong, as the study was never published. Since we know the Glutes never publish anything that might suggest that MSG is toxic, and since the USDA was not even pretending to do an independent study, apparently when the results didn’t come out as desired the report of the study vanished. If not for the twelve-year-old press release we found online that tipped us off, no one outside of the USDA would know about this “partnership” payout.

One might ask why this study was done in the first place? And why done by the USDA?

We think we may know at least part of the answer.

Two years before the USDA/Ajinomoto joint venture, a study from the University of North Carolina clearly linked MSG consumption in people to weight gain. According to epidemiologist Dr. Ka He, those who consume large amounts of MSG increase their risk of being overweight by a whopping 175 percent.

To counter that, Ajinomoto jumped in with a rodent study that was published in the journal Physiology & Behavior, concluding that rats who drank MSG spiked water were lean and healthy. But perhaps comparing their lab rats to humans didn’t seem as effective – at least publicity wise.

So, why not collect a group of human lab animals to study, and have the good name of the USDA associated with Ajinomoto and the safety of MSG?  Ajinomoto found the USDA more than willing to play along.

As we said last year, this is a stunning example of how closely connected industry is with our so-called watchdog federal agencies.

Those interested in learning more about agency/industry cooperation will find interesting material at Industry’s FDA: https://www.truthinlabeling.org/assets/industrys_fda_final.pdf. Those with interest in methods used by the Glutes to come to the foregone conclusion that MSG is a harmless food additive can access How the “MSG is safe” game is played: https://www.truthinlabeling.org/safe.html

What changed in 1957 that triggered the obesity crisis?

Did you ever wonder why consumers didn’t have problems with monosodium glutamate before 1968?   That’s one of the favorite stories told in the ongoing MSG-is-safe-for-you propaganda, and it happens to be true.  True, because of a 1957 invention that enabled production of so much MSG so quickly that it became easily and cheaply available. What had once been a harmless amino acid available and used in limited quantity became poisonous when available and used in great quantity.

Until Dr. Kwok wrote his well-known 1968 letter titled “Chinese Restaurant Syndrome,” physicians passed off reactions to MSG as allergic reactions, and the brain damage caused by MSG wasn’t obvious.

Prior to 1957, the amount of free glutamate in the average diet had been unremarkable.  But that 1957 change (in which Ajinomoto switched from extraction of glutamate from a protein source, a slow and costly method, to a method of bacterial fermentation), allowed them to churn out virtually unlimited amounts of MSG. And Ajinomoto began to market its product aggressively.  Shortly thereafter, food manufacturers found that profits could be increased by utilizing flavor-enhancing additives that contained free glutamate. Over the next two decades, the marketplace became flooded with manufactured/processed free-glutamate in ingredients such as hydrolyzed proteins, yeast extracts, maltodextrin, soy protein isolate, and MSG. And an ever-increasing variety of free glutamate-containing products became readily available to consumers who were being actively solicited.

Prior to 1957, the date of Ajinomoto’s launch of mass-production, there had been no reports of MSG-induced adverse reactions; no studies demonstrating MSG-induced brain damage; no obesity epidemic; no infertility crisis; and the incidence of glutamate-induced abnormalities such as multiple sclerosis (MS), Parkinson’s disease, and autism had not yet begun to skyrocket.

In 1968, eleven years after Ajinomoto began mass producing MSG, the first report of MSG-induced adverse reactions was made public. And soon MSG-induced obesity and infertility would be recognized in young adults who had suffered glutamate-induced brain damage before birth or as newborns.

Why has the USDA gotten cozy with Ajinomoto?

We recently came across this press release issued in 2010: USDA-ARS and Ajinomoto launch sodium glutamate research collaboration. Wait…what?

Why in the world would the U.S. Department of Agriculture be cozying up with Ajinomoto, likely the world’s largest manufacture of monosodium glutamate?

The eleven-year-old release came from the Ajinomoto PR office, describing how this “powerful partnership” will “seek a better understanding of how to improve eating behaviors and human health” (a quote from then Ajinomoto president Masatoshi Ito, who is now listed as chairman of the company).

This “research” collaboration, the release states, “will add to the growing base of science around umami, widely accepted as the fifth basic taste.”

To be sure, the USDA ARS (Agricultural Research Service) does plenty of research. A long list of current collaborations and projects include biological control of coffee berry borer and combating the threat of fusarium wilt to cotton production. But this is something else entirely. An Ajinomoto-funded promotion of its product utilizing the name and resources of a federal agency. And not just any product, but one known to be a neurotoxic (brain damaging), obesity promoting, headache inducing additive, that untold numbers of citizens would like to avoid entirely.

We tracked down the scientist named in the press release, Dr. Kevin Laugero, of the USDA/ARS Western Human Nutrition Research Center (the WHNRC’s mission is described in part as conducting “nutrition interventions” that will help “prevent obesity and related metabolic disorders.”), located at the University of California, Davis campus, and sent him an email. No response.

We then contacted the USDA/ARS public affairs office, which didn’t have very much to say except that perhaps we should contact Ajinomoto to learn more. They also said that sometime in the new year they may be able to reach Dr. Laugero. We are also filing a Freedom of Information Act request with the USDA.

Even if our research hits a brick wall, this is still a stunning illustration of how closely connected industry is with our so-called watchdog federal agencies, which includes, of course, the FDA. Another example of how they’ve been partners in crime for decades.

Stay tuned.

Traces of 450 Pesticides Found in Popular Fruits and Vegetables. And they didn’t even check for the ones grown with MSG.

The Ajinomoto MSG production facility in Eddyville, Iowa

According to an October 15th article in Newsweek, analysis conducted by Consumer Reports on five years of data collected by the Department of Agriculture uncovered traces of more than 450 different pesticides in fruits and vegetables. Some of the residues exceeded what CR considers a “potentially harmful threshold.”

Why, you might ask, would someone who publishes a blog focused on the hazards of Manufactured free Glutamic acid (MfG) in food suddenly be talking about the hazards of pesticides? Unless, of course, some pesticides contain MfG.

Enter a product called AuxiGro. In 1998, Auxein Corporation had applied and was granted permission to spray unregulated amounts of monosodium glutamate combined with MfG from other sources on agricultural products. 

The free glutamate components of MSG and every other flavor-enhancer and protein substitute are excitotoxic – brain damaging — amino acids, known to cause migraine headache, fibromyalgia, asthma, heart irregularities, seizures and more.

We learned of AuxiGro in a curious way. In the late 1990s, an MSG-sensitive friend reported that after eating potatoes (in addition to her otherwise standard diet) she’d had an MSG reaction. Another friend independently told the same story, but his story was about lettuce. What did husband Jack and I believe?  Our friends had gone off the deep end, that’s what we believed.  Maybe too much MSG had gotten to them.

Then came the information that MSG was being sprayed on crops.  Two of the crops that had been used in field tests and then brought to market (prior to approval) were lettuce and potatoes.  This told us that monosodium glutamate sprayed on crops could cause adverse reactions in MSG-sensitive people who ate those crops. 

Not long after AuxiGro was approved for use, Auxein Corporation applied to the National Organic Standards Board (NOSB) for organic certification.  The independently owned and operated Organic Materials Review Institute (OMRI) was in charge of the approval process.  When Jack made his presentation to the NOSB, the OMRI report recommending approval was already in the hands of NOSB board members.  Based on Jack’s presentation which included demonstration of the fact that AuxiGro was a synthetic product, the board denied approval of AuxiGro and L-glutamic acid for use in organic foods.

When the NOSB rejected the application, we assumed that OMRI would cancel its relationship with AuxiGro.  We found, however, that OMRI merely tabled the issue, suggesting to us that they would try again sometime in the future to have AuxiGro approved for use as an organic fertilizer.

During the course of various discussions, we learned that OMRI charged a fee to any company submitting a product for its review prior to receiving an OMRI recommendation to have the product added to the NOSB list of approved organic products.  We also learned that if a product was approved, the producing company would pay OMRI an annual fee as long as the product remained approved.  If there was no NOSB approval, there would be no annual fees paid to OMRI.   Conflict of interest?

AuxiGro came to our attention because it contains MSG.  And although to the best of our knowledge that product is no longer sold and used in the U.S., there are a myriad of fertilizers, pesticides, and plant growth enhancers that contain excitotoxic MfG just as MSG does.  There will be no information about these toxic chemicals on ingredient labels – or anywhere else on a product label for that matter.  But the fruits, grains and vegetables treated with these chemicals will have absorbed them, and will pass them on to the people who consume them.